Table 1.
Variables | Groups | Baseline | After hemorrhage | Two hours post-resuscitation |
---|---|---|---|---|
pH | SHAM | 7.41 ± 0.02 | - | 7.44 ± 0.03a |
GEL | 7.42 ± 0.02 | 7.36 ± 0.05a | 7.48 ± 0.04ab | |
HES 200 | 7.42 ± 0.03 | 7.34 ± 0.05a | 7.46 ± 0.02ab | |
HES 130 | 7.42 ± 0.03 | 7.35 ± 0.03a | 7.4 9 ± 0.03abcd | |
pO2 (Torr) | SHAM | 74.9 ± 5.3 | - | 81.0 ± 9.5 |
GEL | 78.5 ± 4.5 | 109 ± 3.9a | 87.7 ± 11.8b | |
HES 200 | 78.5 ±8.5 | 105.2 ± 12.8a | 91.1 ± 18.8 | |
HES 130 | 79.0 ± 6.5 | 106.5 ± 13.7a | 91.0 ± 5.5abc | |
pCO2 (Torr) | SHAM | 39.0 ± 3.1 | - | 36.7 ± 3.7 |
GEL | 39.8 ± 3.6 | 25.3 ± 3.8a | 29.3 ± 4.0ac | |
HES 200 | 39.6 ± 3.6 | 28.9 ± 3.2a | 30.7 ± 2.7ac | |
HES 130 | 40.2 ± 3.0 | 28.3 ± 4.4a | 28.0 ± 2.7ac | |
Hemoglobin (g/dl) | SHAM | 12.4 ± 0.7 | - | 12.6 ± 0.5 |
GEL | 12.9 ± 1.3 | 10.0 ± 0.6a | 6.8 ± 0.7abc | |
HES 200 | 13 ± 0.4 | 9.7 ± 1.0a | 6.7 ± 0.7abc | |
HES 130 | 13.4 ± 0.5 | 9.8 ± 0.5a | 7.2 ± 0.7abc | |
BE (mmol/L) | SHAM | 0.4 ± 2 | - | 1.3 ± 1.8 |
GEL | 1.5 ± 1.9 | -9.9 ± 2.1a | -1.6 ± 2.1abc | |
HES 200 | 1.5 ± 1.0 | -9.3 ± 2.39a | -1.7 ± 1.8abc | |
HES 130 | 1.8 ± 1.6 | -9.2 ± 2.09a | -1.6 ± 2.4abc |
aP <0.05 versus baseline, bP <0.05 versus after hemorrhage, cP <0.05 versus the sham group, dP <0.05 versus the HES 200 group. Values are means ± SD. BE, base excess; pCO2, partial pressure of carbon dioxide; pO2, partial pressure of oxygen.