Table 4.

Risk of Dialysis or Death with CKD Recognition in EHR the problem list

	HR (95% CI)ESRD (n=21068)**	P-value	HR (95% CI)Mortality (n=25,742)^	P-value
Model 1 – CKD recognition only	12.7 (10.4, 15.5)	<0.001	1.53 (1.41, 1.66)	<0.001
Model 2 – including age, sex, race/ethnicity	9.4 (7.6, 11.6)	<0.001	1.61 (1.48, 1.75)	<0.001
Model 3 – plus insurance	9.0 (7.3, 11.1)	<0.001	1.61 (1.49, 1.75)	<0.001
Model 4 – plus eGFR and comorbidities*	1.18 (0.94, 1.49)	0.15	1.04 (0.95, 1.14)	0.42
Model 5 – plus proteinuria	1.05 (0.81, 1.37)	0.72	0.96 (0.87, 1.07)	0.44

CKD = chronic kidney disease; EHR = electronic health record; HR = Hazards Ratio, 95% CI = 95% confidence interval; ESRD = end stage renal disease; eGFR = estimated glomerular filtration rate

^*diabetes, hypertension, coronary artery disease, congestive heart failure, hyperlipidemia, cerebrovascular disease and eGFR at inception which is 1 year after confirmatory eGFR.

^**Note we only have USRDS follow up until 9/15/2009, patients with confirmatory eGFR after 9/15/2008 are excluded from this analysis.

^{^}Note we only have Social Security Death Index follow up until 10/30/2011.

For model 5 proteinuria subgroup analysis, N=14,922 for ESRD and N=18,385 for mortality