Table 2.
Primary and secondary end points
| |
Before (9 mo) |
Training (10 mo) |
AAS (13 mo) |
Inclinometer (7 mo) |
Oral care (5 mo) |
During (35 mo) |
P value |
|---|---|---|---|---|---|---|---|
| Pts: 401 | Pts: 453 | Pts: 545 | Pts: 294 | Pts: 242 | Pts: 1,534 | ||
| Median length of ICU stay in days (IQR) |
4 (2-7) |
5 (3-7) |
4 (3-6.5) |
4 (2-7) |
4 (3-6) |
4 (3-7) |
0.47 |
| Median days on MV (IQR) |
1 (1-1) |
1 (1-1) |
1 (1-1) |
1 (1-1) |
1 (1-1) |
1 (1-1) |
0.37 |
| Mean days on VM (SD) |
4.1 (11.9) |
2.7 (5.7) |
3.1 (8.9) |
2.4 (4.6) |
3.1 (9.1) |
2.8 (7.4) |
0.05 |
| VAP/1,000 days of MV |
23.9 |
14.8 |
17.8 |
4.8 |
10.9 |
13.5 |
0.005 |
| Mean days of MV/1,000 days of stay (SD) |
507 (128) |
412 (103) |
359 (85) |
342 (99) |
390 (77) |
375 (93) |
0.001 |
| Primary cost of antimicrobial/1,000 days of stay |
€70,612 |
€94,839 |
€39,564 |
€30,153 |
€34,671 |
€52,775 |
0.10 |
| Mortality (%) | 52 (13.0) | 56 (10.4) | 56 (10.3) | 21 (7.1) | 23 (9.5) | 156 (10.2) | 0.10 |
MV, mechanical ventilation, Pts, patients.