Table 2.
Factors independently associated with day-30 mortality.
| sHR | 95% CI | P value | |
|---|---|---|---|
| Natremia | |||
| Severe hyponatremia | 1.27 | (1.01-1.60) | 0.040 |
| Moderate hyponatremia | 1.18 | (1.002-1.40) | 0.047 |
| Mild hyponatremia | 1.08 | (0.95-1.22) | 0.23 |
| Borderline hyponatremia | 1.09 | (0.97-1.24) | 0.15 |
| Normal natremia | 1 | (Ref) | - |
| Borderline hypernatremia | 1.09 | (0.97-1.24) | 0.15 |
| Mild hypernatremia | 1.34 | (1.14-1.57) | 0.0003 |
| Moderate hypernatremia | 1.51 | (1.15-1.99) | 0.003 |
| Severe hypernatremia | 2.64 | (2.00-3.48) | < 0.0001 |
| DFLST* | 3.24 | (2.90-3.62) | < 0.0001 |
| Intoxication as reason for ICU admission | 0.21 | (0.13-0.34) | < 0.0001 |
| Chronic cardiac dysfunction | 1.26 | (1.13-1.41) | < 0.0001 |
| Immunocompromised patient | 1.30 | (1.17-1.45) | < 0.0001 |
| Age > 64 yrs | 1.56 | (1.43-1.71) | < 0.0001 |
| SOFA score (per point)* | 1.21 | (1.20-1.23) | < 0.0001 |
(Subdistribution hazard ratios (sHR) and 95% confidence intervals (95% CI)). *DFLST, decision to forgo life-sustaining treatments; SOFA, Sequential Organ Failure Assessment, which can range from 0 to 24.