Figure 4.

Prediction corrected-visual predictive check (PC-VPC) for plasma glucose level (A) and plasma lactate level (B) observations versus time in minutes. The green lines depict the 5th, 50th and 95th percentiles of observed data; the areas represent the 95% confidence interval around the simulated percentiles. Blue color represent the 5th and the 95th percentile of the predicted plasma glucose level and lactate level versus time and pink color represent the median predicted plasma glucose level and lactate level versus time. Time 0 min represents the starting time of epinephrine infusion.