Table 3.
Factors associated with impairment in renal function after surgery
| RR | 95% CI | P -value | OR | 95% CI | P -value | |
|---|---|---|---|---|---|---|
|
Multiple surgery |
1.83 |
1.54, 2.18 |
<0.001 |
4.16 |
2.98, 5.80 |
<0.001 |
|
Vancomycin administration |
1.57 |
1.37, 1.81 |
<0.001 |
2.63 |
2.07, 3.34 |
<0.001 |
|
Aminoglycoside administration |
1.23 |
1.07, 1.41 |
0.004 |
1.44 |
1.13, 1.83 |
0.004 |
|
Vancomycin:aminoglycoside interaction |
1.54 |
1.34, 1.76 |
<0.001 |
2.62 |
2.08, 3.31 |
<0.001 |
|
Contrast agent |
1.33 |
1.18, 1.51 |
<0.001 |
1.70 |
1.37, 2.12 |
<0.001 |
|
Transfusion |
1.62 |
1.27, 2.07 |
<0.001 |
2.38 |
1.55, 3.63 |
<0.001 |
|
Pre-operative hemoglobin (<10 g/dl) |
1.39 |
1.15, 1.67 |
0.001 |
1.89 |
1.34, 2.66 |
<0.001 |
| Age (>65 y) | 0.57 | 0.47, 0.70 | <0.001 | 0.41 | 0.30, 0.57 | <0.001 |
The variable importance measure for the risk factors associated with post-operative renal function impairment was performed after adjusting for all other covariates. RR, relative risk, OR, odds ratio.