. Author manuscript; available in PMC: 2014 Jun 13.

Published in final edited form as: Open Transplant J. 2011 Jan 1;5:15–22. doi: 10.2174/1874418401105010015

Table 1.

Effect of Warm Ischemia Times (WIT), alone or in Combination with 24hrs Cold Storage (CS) in UW-Solution, on Parameters of Renal Function and Preservation Injury

WIT (min)/ CS (UW)	Perfusate flow (ml/min/g)	RVR (mmHg/ml/min/g)	VO₂ (ml/min/100g)	Urine Flow (μl/min/g)
0 h (Control)	26.9 ± 4.4	1.7 ± 0.5	1.75 ± 0.28	193 ± 29
WI 60min	14.8 ± 2.8^*	5.6 ± 2.1	0.6 ± 0.1^*	11.6 ± 3.8^*
WI 90min	6.3 ± 0.9^*	22.3 ± 4.8^*	0.5 ± 0.1^*	18.7 ± 3.2^*
WI 30/CS	17.1 ± 2.0^*	1.9 ± 0.4	0.7 ± 0.2^*	43.0 ± 11.2^*
WI 60/CS	9.8 ± 2.6^*	26.1 ± 11.5^*^#	0.5 ± 0.1^*	20.3 ± 9.7^*

WIT (min)/ CS (UW)	GFR (μl/min/g)	Protein excretion (μg/g)	LDH (U/L/g)	TTW (mg H₂O/ mg dry weight)
0 h (Control)	632 ± 142	1.4 ± 0.5	2592 ± 489	3.37 ± 0.28
WI 60min	17.9 ± 6.7^*	511.6 ± 89.5^*	4211 ± 1101	4.11 ± 0.19
WI 90min	18.8 ± 2.2^*	433.5 ± 73.0^*	6375 ± 579^*	5.08 ± 0.13^*
WI 30/CS	54 ± 3	135 ± 63^*	4431 ± 465	4.03 ± 0.21
WI 60/CS	22 ± 13^*	492 ± 91^*^#	6682 ± 937^*	5.21 ± 0.36^*

Values are mean ± Standard Deviation, n=8,

P< 0.05 relative to control,

P<0.05 relative to WI 30/CS.