Table 2.
Respiratory and hemodynamic parameters during the baseline measurements (pre D), the spontaneous breathing trial (D(f)) and (D(l)) and after reconnection to the ventilator (post D) for all patients
| Parameter | Time | All ( n = 18) | Failure ( n = 6) | Success ( n = 12) |
|---|---|---|---|---|
| VT (ml) |
pre D |
383 (339/508)c |
340 (308/378) |
423 (373/534) |
| D (f) |
337 (266/551)c |
210 (167/470) |
345 (297/475) |
|
| D (l) |
318 (220/453)c |
198 (176/395) |
343 (300/452) |
|
| post D |
409 (361/496)c |
383 (344/462) |
407 (362/514) |
|
| RR (bpm) |
pre D |
21 (16/29) |
25 (20/30) |
22 (15/26) |
| D (f) |
24 (20/29) |
30 (25/38)a |
21 (17/24)a |
|
| D (l) |
22 (20/30) |
29 (23/37)a |
21 (17/22)a |
|
| post D |
21 (17/24) |
19 (17/21) |
22 (18/23) |
|
| VT/EAdi |
pre D |
46 (29/120)d |
45 (38/127)c |
43 (25/92) |
| D (f) |
21 (11/43)d |
14 (12/18)c |
35 (15/70) |
|
| D (l) |
16 (8/27)d |
14 (9/15)c |
24 (12/53) |
|
| post D |
45 (27/68)d |
41 (36/62)c |
45 (23/64) |
|
| RR/VT |
pre D |
49 (37/81)c |
77 (54/96) |
48 (33/58) |
| D (f) |
61 (47/109)c |
127 (62/286) |
59 (44/74) |
|
| D (l) |
71 (51/118)c |
135 (74/250) |
63 (40/75) |
|
| Post D |
50 (33/71)c |
51 (37/57) |
50 (40/67) |
|
| HF (bpm) |
Pre D |
84 (79/91)b |
84 (81/89)b |
84 (76/88) |
| D (f) |
89 (79/102)b |
87 (79/100)b |
85 (80/95) |
|
| D (l) |
92 (78/103)b |
100 (86/111)b |
89 (77/95) |
|
| Post D |
88 (78/100)b |
86 (79/97)b |
89 (78/94) |
|
| BP syst (mm Hg) |
Pre D |
126 (111/142)b |
125 (111/151)c |
126 (118/139) |
| D (f) |
144 (121/151)b |
162 (145/171)c |
138 (116/147) |
|
| D (l) |
134 (121/150)b |
155 (137/171)c |
125 (121/145) |
|
| post D |
127 (116/140)b |
133 (117/140)c |
126 (121/133) |
|
| MAAS |
pre D |
3 (2/3)d |
2 (2/3)b |
3 (2/3) |
| D (f) |
3 (2/4)d |
3 (2/4)b |
3 (3/3) |
|
| D (l) |
3 (3/5)d |
5 (3/5)b |
3 (3/3) |
|
| post D |
3 (2/3)d |
2 (2/3)b |
3 (2/3) |
|
| EAdimax (μV) |
pre D |
9 (5/12)c |
8 (4/9)c |
10 (7/19) |
| D (f) |
11 (10/29)c |
19 (12/27)c |
10 (8/32) |
|
| D (l) |
18 (11/29)c |
26 (16/29)c |
13 (9/26) |
|
| post D | 10 (8/15)c | 9 (6/12)c† | 9 (7/18) |
During disconnection, weaning indices and clinical parameters changed significantly over all patients. aP < 0.05 (tested: failure versus success; Mann–Whitney U test). bP < 0.05 (tested: all, failure, success; Friedman ANOVA); cP < 0.01 (tested: all, failure, success; Friedman ANOVA); dP < 0.001 (tested: all, failure, success; Friedman ANOVA); data displayed as median with 25%/75% quartiles; pre D, baseline values before spontaneous breathing trial (SBT); D(f), first values after disconnection from the ventilator (after about 5minutes); D(l), last values before reconnecting to the ventilator; post D, values about 5 minutes after reconnecting to the ventilator; VT (ml), tidal volume in milliliter, values estimated by respiratory inductive plethysmography (RIP) printed in italics; RR (bpm), respiratory rate in beats per minute; VT/EAdi, tidal volume/EAdimax quotient in milliliters/μV; RR/VT (L), respiratory rate/tidal volume quotient in beats per minute/liter; HF, heart frequency in beats per minute; BP syst, systolic blood pressure in mm Hg; MAAS, Motor Activity Assessment Scale.