Table 3.

Serum Epoxide/Diol ratios. The serum concentration of epoxy-FA was divided by the concentration of the corresponding dihydroxy-FA on individual level. The mean and SD of the ratio is shown for the total study population and normo- vs. hyperlipidemic groups.

Parent FA	Epoxide:Diol	Total population (n=40)			Normolipidemic group (n=20)			Hyperlipidemic group (n=20)
		mean	±	SD	mean	±	SD	mean	±	SD	P1 (normo vs. hyper)
LA	9(10)-EpOME: 9,10-DiHOME	2.54	±	0.43	2.02	±	0.49	3.06	±	0.69	0.226
	12(13)-EpOME: 12,13-DiHOME	1.23	±	0.14	0.97	±	0.16	1.48	±	0.21	0.063
AA	8(9)-EpETrE: 8,9-DiHETrE	1.94	±	0.19	2.19	±	0.28	1.70	±	0.25	0.198
	11(12)-EpETrE: 11,12-DiHETrE	2.50	±	0.25	2.28	±	0.27	2.71	±	0.43	0.406
	14(15)-EpETrE: 14,15-DiHETrE	1.88	±	0.21	1.77	±	0.21	1.99	±	0.36	0.596
ALA	9(10)-EpODE: 9,10-DiHODE	12.2	±	1.98	8.05	±	2.08	16.3	±	3.15	0.035
	12(13)-EpODE: 12,13-DiHODE	4.30	±	0.55	3.14	±	0.51	5.46	±	0.92	0.035
	15(16)-EpODE: 15,16-DiHODE	0.37	±	0.02	0.34	±	0.03	0.40	±	0.04	0.226
EPA	11(12)-EpETE: 11,12-DiHETE	3.89	±	0.44	3.57	±	0.53	4.22	±	0.72	0.475
	14(15)-EpETE: 14,15-DiHETE	2.69	±	0.32	2.38	±	0.35	3.0	±	0.54	0.342
	17(18)-EpETE: 17,18-DiHETE	0.68	±	0.06	0.62	±	0.07	0.75	±	0.10	0.304
DHA	10(11)-EpDPE: 10,11-DiHDPE	4.72	±	0.52	5.07	±	0.75	4.37	±	0.73	0.506
	13(14)-EpDPE: 13,14-DiHDPE	2.51	±	0.28	2.37	±	0.35	2.64	±	0.43	0.623
	16(17)-EpDPE: 16,17-DiHDPE	1.89	±	0.22	1.82	±	0.29	1.96	±	0.33	0.756
	19(20)-EpDPE: 19,20-DiHDPE	0.56	±	0.07	0.46	±	0.06	0.65	±	0.13	0.164

All variables were normally distributed.

¹Significant differences in group means were determined by independent sample t-test.