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. 2014 Jun 13;9(6):e96863. doi: 10.1371/journal.pone.0096863

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© 2014 Moffett et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A: Representative islets showing glucagon (green) and PC2 (red, indicated by block arrows), glucagon (green) and PC1/3 (red, indicated by block arrows) immunoreactivity from non-pregnant and pregnant C57BL/6, GLP-1RKO and GIPRKO mice are shown. B: PC2/glucagon colocalization, expressed in terms of Pearson's coefficient of colocalization. C: PC1/3/glucagon colocalization, expressed in terms of Pearson's coefficient of colocalization. Values are mean ± SEM of 6 observations. ^Δp<0.05 compared to respective non-pregnant controls. ^*p<0.05 compared to non-pregnant C57BL/6 mice.