Table 4.
Pre-ICU, all patients | Pre-ICU, survivors (6 months) | ICU discharge | Hospital discharge | 3 months after ICU discharge | 6 months after ICU discharge |
General population (61- to 70-year-old age group) |
Differences between pre-ICU survivors (n = 325) and pre-ICU non-survivors (n = 168)a |
Differences between pre-ICU survivors and general populationb | Differences between pre-ICU (n = 325) and 6 months after ICU discharge (n = 325)c | Differences between 6 months after ICU discharge and general populationb | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Number | 577 | 325 | 448 | 367 | 338 | 325 | P value | Effect sizes |
P value | Effect sizes |
Wilks's lambda | Effect sizes |
P value | Effect sizes |
|
PCS | 41.5 ± 13.6 | 44.0 ± 12.9 | 26.6 ± 6.5 | 32.5 ± 9.2 | 36.8 ± 10.5 | 39.1 ± 11.1 | - | < 0.001d | 0.57 | - | - | < 0.001d | 0.38 | - | - |
MCS | 48.5 ± 10.3 | 50.1 ± 9.9 | 46.1 ± 9.3 | 47.9 ± 9.5 | 49.7 ± 10.9 | 50.7 ± 10.9 | - | < 0.001d | 0.35 | - | - | 0.241 | 0.06 | - | - |
PF | 59.6 ± 34.6 | 66.6 ± 33.2 | 6.4 ± 12.9 | 30.8 ± 26.4 | 49.0 ± 32.4 | 54.3 ± 31.8 | 71.7 ± 25.6 | < 0.001d | 0.59 | 0.006 | 0.20 | < 0.001d | 0.37 | < 0.001d | 0.68 |
RP | 52.5 ± 47.4 | 60.9 ± 46.7 | 14.4 ± 32.5 | 19.6 ± 35.7 | 28.9 ± 40.5 | 39.7 ± 45.6 | 67.3 ± 40.9 | < 0.001d | 0.54 | 0.014 | 0.16 | < 0.001d | 0.45 | < 0.001d | 0.67 |
BP | 79.0 ± 26.9 | 80.2 ± 27.3 | 75.1 ± 25.0 | 82.1 ± 22.8 | 80.7 ± 24.0 | 84.0 ± 22.2 | 70.5 ± 24.6 | 0.238 | 0.14 | < 0.001d | 0.39 | 0.033d | 0.14 | < 0.001d | 0.55 |
GH | 50.9 ± 30.3 | 57.9 ± 28.9 | 31.1 ± 19.6 | 38.8 ± 27.4 | 44.7 ± 26.4 | 46.8 ± 24.9 | 61.7 ± 20.2 | < 0.001d | 0.57 | 0.019 | 0.19 | < 0.001d | 0.38 | < 0.001d | 0.74 |
VT | 53.6 ± 24.1 | 58.9 ± 24.2 | 32.7 ± 15.9 | 44.9 ± 18.2 | 55.9 ± 22.8 | 58.9 ± 21.7 | 67.7 ± 19.6 | < 0.001d | 0.59 | < 0.001d | 0.45 | 0.610 | 0.10 | < 0.001d | 0.36 |
SF | 71.8 ± 24.7 | 77.5 ± 24.6 | 52.1 ± 22.5 | 60.4 ± 24.8 | 69.1 ± 27.8 | 72.5 ± 24.8 | 82.0 ± 24.6 | < 0.001d | 0.56 | 0.001d | 0.18 | 0.011d | 0.20 | < 0.001d | 0.39 |
RE | 74.8 ± 40.9 | 79.3 ± 39.0 | 60.9 ± 44.3 | 68.2 ± 45.6 | 70.0 ± 43.2 | 75.9 ± 40.9 | 81.1 ± 35.0 | 0.010d | 0.29 | 0.412 | 0.05 | 0.383 | 0.08 | 0.027 | 0.15 |
MH | 67.5 ± 16.7 | 70.9 ± 15.9 | 56.9 ± 11.5 | 63.1 ± 13.0 | 67.6 ± 16.1 | 69.2 ± 21.5 | 76.9 ± 17.9 | < 0.001d | 0.50 | < 0.001d | 0.34 | 0.461 | 0.08 | < 0.001d | 0.43 |
Effect sizes of at least 0.20, at least 0.50, and greater than 0.80 correspond to small, medium, and large, respectively. Values are presented as mean ± standard deviation (SD). aUnivariate analysis of variance with Bonferroni correction P < 0.05 significant. bOne-sample t test. cGeneral linear model repeated measures with Bonferroni correction P < 0.05 significant. dP value significant after Bonferroni correction (P 0.05/10 = P = 0.005 = significant). SF-36 (Medical Outcomes Study 36-item Short-Form) dimension scores range from 0 to 100. Physical component score (PCS) and mental component score (MCS) are converted to mean 50 (SD 10). BP, bodily pain; GH, general health; ICU, intensive care unit; MH, mental health; PF, physical functioning; RE, role limitation due to emotional problems; RP, role limitation due to physical problems; SF, social functioning; VT, vitality.