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. 2013 Jan 28;17(1):R17. doi: 10.1186/cc12491

Table 4.

Health-related quality of life in surviving patients without acute kidney injury and comparison with general population

Pre-ICU, all patients Pre-ICU, survivors (6 months) ICU discharge Hospital discharge 3 months after ICU discharge 6 months
after ICU
discharge
General population
(61- to 70-year-old age group)
Differences between pre-ICU survivors (n = 325) and pre-ICU non-survivors
(n = 168)a
Differences between pre-ICU survivors and general populationb Differences between pre-ICU (n = 325) and 6 months after ICU discharge (n = 325)c Differences between 6 months after ICU discharge and general populationb
Number 577 325 448 367 338 325 P value Effect
sizes
P value Effect
sizes
Wilks's lambda Effect
sizes
P value Effect
sizes

PCS 41.5 ± 13.6 44.0 ± 12.9 26.6 ± 6.5 32.5 ± 9.2 36.8 ± 10.5 39.1 ± 11.1 - < 0.001d 0.57 - - < 0.001d 0.38 - -

MCS 48.5 ± 10.3 50.1 ± 9.9 46.1 ± 9.3 47.9 ± 9.5 49.7 ± 10.9 50.7 ± 10.9 - < 0.001d 0.35 - - 0.241 0.06 - -

PF 59.6 ± 34.6 66.6 ± 33.2 6.4 ± 12.9 30.8 ± 26.4 49.0 ± 32.4 54.3 ± 31.8 71.7 ± 25.6 < 0.001d 0.59 0.006 0.20 < 0.001d 0.37 < 0.001d 0.68

RP 52.5 ± 47.4 60.9 ± 46.7 14.4 ± 32.5 19.6 ± 35.7 28.9 ± 40.5 39.7 ± 45.6 67.3 ± 40.9 < 0.001d 0.54 0.014 0.16 < 0.001d 0.45 < 0.001d 0.67

BP 79.0 ± 26.9 80.2 ± 27.3 75.1 ± 25.0 82.1 ± 22.8 80.7 ± 24.0 84.0 ± 22.2 70.5 ± 24.6 0.238 0.14 < 0.001d 0.39 0.033d 0.14 < 0.001d 0.55

GH 50.9 ± 30.3 57.9 ± 28.9 31.1 ± 19.6 38.8 ± 27.4 44.7 ± 26.4 46.8 ± 24.9 61.7 ± 20.2 < 0.001d 0.57 0.019 0.19 < 0.001d 0.38 < 0.001d 0.74

VT 53.6 ± 24.1 58.9 ± 24.2 32.7 ± 15.9 44.9 ± 18.2 55.9 ± 22.8 58.9 ± 21.7 67.7 ± 19.6 < 0.001d 0.59 < 0.001d 0.45 0.610 0.10 < 0.001d 0.36

SF 71.8 ± 24.7 77.5 ± 24.6 52.1 ± 22.5 60.4 ± 24.8 69.1 ± 27.8 72.5 ± 24.8 82.0 ± 24.6 < 0.001d 0.56 0.001d 0.18 0.011d 0.20 < 0.001d 0.39

RE 74.8 ± 40.9 79.3 ± 39.0 60.9 ± 44.3 68.2 ± 45.6 70.0 ± 43.2 75.9 ± 40.9 81.1 ± 35.0 0.010d 0.29 0.412 0.05 0.383 0.08 0.027 0.15

MH 67.5 ± 16.7 70.9 ± 15.9 56.9 ± 11.5 63.1 ± 13.0 67.6 ± 16.1 69.2 ± 21.5 76.9 ± 17.9 < 0.001d 0.50 < 0.001d 0.34 0.461 0.08 < 0.001d 0.43

Effect sizes of at least 0.20, at least 0.50, and greater than 0.80 correspond to small, medium, and large, respectively. Values are presented as mean ± standard deviation (SD). aUnivariate analysis of variance with Bonferroni correction P < 0.05 significant. bOne-sample t test. cGeneral linear model repeated measures with Bonferroni correction P < 0.05 significant. dP value significant after Bonferroni correction (P 0.05/10 = P = 0.005 = significant). SF-36 (Medical Outcomes Study 36-item Short-Form) dimension scores range from 0 to 100. Physical component score (PCS) and mental component score (MCS) are converted to mean 50 (SD 10). BP, bodily pain; GH, general health; ICU, intensive care unit; MH, mental health; PF, physical functioning; RE, role limitation due to emotional problems; RP, role limitation due to physical problems; SF, social functioning; VT, vitality.