Table 1.
Influx of neutrophils in bronchiolar lavage fluid of control or anti-HMGB1-treated mice
| Time point (t) | Control IgG2b | Anti-HMGB1 |
|---|---|---|
| t = 6 h |
508 (390 to 1169) |
520 (207 to 736) |
| t = 24 h |
434 (391 to 580) |
665 (450 to 934) |
| t = 48 h |
1376(1054 to 1796) |
1339 (1147 to 1770) |
| t = 72 h | 600 (516 to 891) | 519(425 to 841) |
Neutrophil numbers (×1,000/ml) in BAL fluid at 6, 24, 48 and 72 hours after intranasal S. aureus infection in control and anti-HMGB1-treated mice. Data are medians (interquartile ranges); n = 7 to 8 mice per group per time point. HMGB1, High mobility group box 1.