Table 2.

Influx of neutrophils in bronchiolar lavage fluid of wild-type, tlr4 ^−/− or Rage ^−/− mice

Time point (t)	Wild-type	Tlr4 −/−	Rage −/−
t = 6 h	239 (217 to 310)	397 (221 to 535)	526 (350 to 647)
t = 24 h	298 (250 to 380)	236 (196 to 275)	342 (262 to 404)
t = 48 h	429 (218 to 652)	522 (421 to 756)	395 (314 to 541)
t = 72 h	146 (99 to 190)	90 (81 to 132)	76 (47 to 104)*

Neutrophil numbers (×1000/ml) in bronchiolar lavage fluid at 6, 24, 48 and 72 hours after intranasal S. aureus infection in wild-type (Wt), Toll-like receptor (tlr)4^−/− and Receptor for advanced glycation end products (Rage)^−/− mice. Data are medians (interquartile ranges); n = 7 to 8 mice per group per time point. ^*P <0.05 versus Wt mice at the same time point.