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. 2014 Jun 13;9(6):e99491. doi: 10.1371/journal.pone.0099491

Figure 5. Alignment of an A. nidulans ORF to known TERT motifs.

Figure 5

The ANID_03753.1 predicted protein sequence (AN_TERT) was aligned to the TERT sequence from mouse (MOUSE_TERT, accession number O70372) and S. pombe (SP_TERT, accession number O13339) using the Align program in Vector NTI (Invitrogen). The region of the alignment including AN_TERT residues 601 through 1120 were selected and are shown. The conserved telomerase reverse transcriptase motifs (Motif T, 1, 2, Motif A, Motif B, Motif C, Motif D and Motif E) are indicated above the aligned sequences. Residues identical in all three sequences are in shown with dark shading, whereas sequences that are similar or identical in only two sequences are shown in lighter shading.