Table 3.
The factors associated with 6-month mortality in patients with aneurysmal subarachnoid hemorrhage.
| Non-survival group (n = 31) | Survival group (n = 231) | Univariate analysis P value | |
|---|---|---|---|
| Sex (male/female) | 13/18 | 99/132 | 0.922 |
| Age (years) | 44.4 ± 12.0 | 43.5 ± 12.2 | 0.695 |
| WFNS score on admission | 4 (1) | 2 (2) | < 0.001 |
| Fisher score on admission | 4 (1) | 2 (1) | < 0.001 |
| Aneurysmal location | 0.974 | ||
| Posterior communication artery | 7 (22.6%) | 71 (30.7%) | |
| Internal carotid artery | 6 (19.4%) | 34 (14.7%) | |
| Anterior communication artery | 7 (22.6%) | 52 (22.5%) | |
| Middle cerebral artery | 5 (16.1%) | 34 (14.7%) | |
| Anterior cerebral artery | 4 (12.9%) | 26 (11.3%) | |
| Posterior cerebral artery | 1 (3.2%) | 9 (3.9%) | |
| Vertebral artery | 1 (3.2%) | 5 (2.2%) | |
| Surgery | 20 (64.5%) | 143 (61.9%) | 0.778 |
| Acute hydrocephalus | 20 (64.5%) | 59 (34.2%) | < 0.001 |
| Intraventricular hemorrhage | 27 (87.1%) | 28 (12.1%) | < 0.001 |
| External ventricular drain | 28 (90.3%) | 63 (27.3%) | < 0.001 |
| Vasospasm | 28 (90.3%) | 84 (36.4%) | < 0.001 |
| CT ischemia | 12 (38.7%) | 27 (11.7%) | < 0.001 |
| Admission time (h) | 4.0 (6.0) | 4.0 (4.0) | 0.826. |
| Plasma-sampling time (h) | 6.0 (7.4) | 5.4 (6.4) | 0.398 |
| Seizure | 7 (22.5%) | 30 (13.0%) | 0.174 |
| Systolic arterial pressure (mmHg) | 130 (36) | 130 (30) | 0.373 |
| Diastolic arterial pressure (mmHg) | 81 (21) | 80 (22) | 0.421 |
| Mean arterial pressure (mmHg) | 101 (23) | 97 (25) | 0.257 |
| Heart rate (beats/min) | 81 (23) | 80 (36) | 0.602 |
| Body temperature (°C) | 36.7 (1.9) | 36.5 (0.9) | 0.551 |
| Respiratory rate (respirations/min) | 19 (3) | 18 (5) | 0.935 |
| Blood oxygen saturation (%) | 88 (7) | 88 (5) | 0.344 |
| Blood white blood cell count (×109/L) | 6.5 (6.1) | 7.5 (4.0) | 0.566 |
| Blood hemoglobin level (g/L) | 122 (37) | 125 (37) | 0.129 |
| Blood platelet count (×109/L) | 183 (34) | 173 (56) | 0.269 |
| Blood glucose level (mmol/L) | 10.7 (5.9) | 9.1 (2.6) | 0.003 |
| Blood sodium level (mmol/L) | 135 (11) | 136 (7) | 0.673 |
| Blood potassium level (mmol/L) | 3.8 (1.3) | 3.7 (0.9) | 0.926 |
| Prothrombin time (s) | 14.5 (3.2) | 14.6 (4.1) | 0.659 |
| Thrombin time (s) | 18.4 ± 2.9 | 18.9 ± 3.3 | 0.369 |
| Partial thromboplastin time (s) | 39.5 (11.8) | 39.4 (10.6) | 0.476 |
| Plasma C-reactive protein level (mg/L) | 8.1 (6.5) | 6.2 (3.6) | 0.013 |
| Plasma fibrinogen level (g/L) | 4.8 (4.2) | 3.9 (3.8) | 0.036 |
| Plasma D-dimer level (mg/L) | 2.3 (1.2) | 1.8 (1.1) | 0.014 |
| Plasma gelsolin level (mg/L) | 49.0 (17.9) | 70.3 (25.5) | < 0.001 |
Numerical variables were presented as median (interquartile range) or mean ± standard deviation. Categorical variables were expressed as counts (percentage). Numerical variables were analyzed by Mann-Whitney U-test or unpaired Student t test. Categorical variables were analyzed by chi-square test or Fisher exact test.
n, number of patients; WFNS, World Federation of Neurological Surgeons.