Table 2.
Erythrocyte selenium concentration, GPx1 activity, protein carbonyl and mortality according to Pro198Leu polymorphism genotype
| Variables | Pro/Pro (n = 57) | Pro/Leu (n = 40) | Leu/Leu (n = 7) | P value |
|---|---|---|---|---|
| Erythrocyte Se, (μmol/L) |
0.41 ± 0.15 |
0.42 ± 0.14 |
0.46 ± 0.12 |
0.655 |
| Protein carbonyl, (nmol/ml) |
13.5 (4.6 - 24.2) |
7.5 (4.4 - 25.7) |
5.3 (3.1 - 17.5) |
0.403 |
| GPx1, (U/g Hb) |
28.5 (19.8 - 36.7) |
31.1 (27.7 - 41.0) |
35.9 (24.7 - 51.5) |
0.045 |
| SOFA score |
8.8 ± 2.6 |
10.4 ± 4.3 |
9.1 ± 1.9 |
0.067 |
| ICU mortality, number (%) |
27 (47) |
26 (65) |
4 (57) |
0.227 |
| Hospital mortality, number (%) | 31 (54) | 30 (75) | 5 (71) | 0.105 |
Data are expressed as the mean ± standard deviation (SD), median (including the lower and upper quartiles) or percentage. GPx1, glutathione peroxidase activity; Se, selenium concentration; SOFA, sequential organ failure assessment; ICU, intensive care unit.