Table 3.
Narrative synthesis tabulation of candidate risk factor theme and subtheme clusters
|
Theme |
Risk factors included |
|---|---|
| Subthemes | |
|
Patient characteristics | |
| Baseline demographics |
Age |
| Gender | |
| Obesity | |
| Emergent/surgical status | |
| Presenting diagnosis |
Etiology |
| Cirrhosis | |
| Liver dysfunction | |
| Gastrointestinal bleed | |
| Ileus | |
| Sepsis/infections | |
| White blood cell count | |
| Abdominal surgery | |
| Pancreatitis | |
| Amylase level | |
| Calcium level | |
| C-reactive protein level | |
| Albumin | |
| Disease severity |
APACHE-II score |
| SOFA score | |
| Glasgow Coma Scale score | |
| Revised trauma score | |
| Injury severity score | |
| Charlson comorbidity score | |
| Ranson score | |
| Glasgow-Imrie score | |
|
Systemic physiology | |
| Shock/hypotension |
Mean arterial pressure |
| Systolic blood pressure | |
| Shock | |
| Hypotension | |
| Vasopressor use | |
| Capillary leak index | |
| Central venous pressure | |
| GAPCO2 | |
| Urine output | |
| Cardiac index | |
| Hematocrit | |
| Hemoglobin | |
| Metabolic derangement/organ failure |
Base deficit |
| Blood glucose | |
| International normalized ratio | |
| Hypothermia | |
| Acidosis | |
| Serum creatinine | |
| Respiratory status/failure |
Respiratory failure |
| Acute respiratory distress syndrome | |
| Mechanical ventilation | |
| Positive end-expiratory pressure | |
| Peak airway pressure | |
| Respiratory rate | |
|
Fluid resuscitation | |
| Crystalloid resuscitation |
Pre-ICU crystalloid |
| Pre-hospital crystalloid | |
| Emergency department fluid | |
| 24-hour fluid balance | |
| Fluid balance | |
| Fluid resuscitation | |
| Fluid collections | |
| Non-crystalloid resuscitation | Poly-transfusion |
| Packed red blood cell units | |
| Crystalloid: packed red blood cell ratio | |
APACHE, acute physiology and chronic health evaluation; SOFA, sequential organ failure assessment; GAPCO2, gastric mucosal CO2 minus end tidal CO2.