Table 4.
Performance of the new termination-of-resuscitation rule for predicting one-month unfavorable neurological outcome a
| |
Development group (
N
= 390,577) |
Validation group (
N
= 105,030) |
||
|---|---|---|---|---|
| Variables |
Fulfilled 3/3 criteria |
Did not fulfill criteria |
Fulfilled 3/3 criteria |
Did not fulfill criteria |
| ( n = 223,023, 57.1%) | ( n = 167,554, 42.9%) | ( n = 60,205, 57.3%) | ( n = 44,825, 42.7%) | |
| Unfavorable (CPC categories 3 to 5), n |
222,642 |
161,691 |
60,132 |
42,751 |
| Favorable (CPC categories 1 and 2), n |
381 |
5,863 |
73 |
2,074 |
| Sensitivity (95% CI) |
0.579 (0.578 to 0.581) |
0.585 (0.582 to 0.588) |
||
| Specificity (95% CI) |
0.939 (0.933 to 0.945) |
0.966 (0.958 to 0.973) |
||
| PPV (95% CI) |
0.998 (0.998 to 0.999) |
0.999 (0.999 to 0.999) |
||
| NPV (95% CI) |
0.035 (0.034 to 0.036) |
0.046 (0.044 to 0.048) |
||
| Area under the ROC curve (95% CI) | 0.922 (0.921 to 0.923) | 0.942 (0.941 to 0.944) | ||
aCPC, Cerebral Performance Category; CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value; ROC, receiver operating characteristic.