. Author manuscript; available in PMC: 2015 Jan 1.

Published in final edited form as: J Pharm Biomed Anal. 2013 Jul 24;88:174–179. doi: 10.1016/j.jpba.2013.07.010

Table 2.

LC/MS accurate mass determination for endoxifen and impurities.

Peak no.	Retention time (min)^a	Area% of major component	Sample conc.	Retention time (min)^b	Exact mass of [M + H] ⁺ Ion (amu)	Formula assignment of neutral species	Mass error of assigned formula (ppm)
1	8.940	0.12	0.165 mg/mL	8.940	360.1970	C₂₄H₂₅NO₂	−3.32
2	9.400	2.28	0.0165 mg/mL	9.393	374.2118	C₂₅H₂₇NO₂	−0.75
3	10.540	100	0.165 μg/mL	10.533	374.2123	C₂₅H₂₇NO₂	−2.11

In 0.165 mg/mL sample, UV detection.

For sample used for accurate mass determination, UV detection.