Skip to main content
. 2014 Jun 13;9(6):e99720. doi: 10.1371/journal.pone.0099720

Table 2. Summary of the most significantly-overrepresented pathways of the differentially-expressed genes in muscle between High and Low groups for fatty acid composition traits.

Babelomics IPA
Category Genes P-value Category Genes P-value
Metabolism of Lipids and Lipoproteins SCD, ACADVL, ACOX2, IDH1, IDI1, ALB 5.12×10−4 Nitric Oxid Signalling in the Cardiovascular System BDKRB2, PIK3R3, PRKG1, PLN, ITPR2, PIK3R1, ATP2A2 7.75×10−7
Alanine, Aspartate and Glutamate Metabolism ABAT, GOT1, ASNS 6.38×10−4 eNOS Signalling BDK4B2, PIK3R3, AQP7, PRKG1, ITPR2, PIK3R1, CHRNA9, AQP4 2.34×10−6
PPAR Signalling Pathway ACOX2, AQP7, FABP3, SCD 7.25×10−4 Clathrin-mediated Endocytosis Signalling PIK3R3, ALB, CD2AP, TF, PIK3R1, TFRC, ITGB6, FGF1 2.95×10−5
Insulin Signalling Pathway GYS2, PIK3R1, TRIP10, PIK3R3, PPP1R3C 1.00×10−3 ILK Signalling PIK3R3, FOS, RND3, PIK3R1, ITGB6, MYL6B, MYH7B, ACTN3 2.95×10−5
Hemostasis ANGPT1, PIK3R1, ALDOA, ITPR2, PLEK, TF, ALB 1.64×10−3 CXCR4 Signalling PIK3R3, FOS, RND3, ITPR2, PIK3R1, MYL6B 4.79×10−4