Table 1.
Characteristics | Normal | RVH | RVH+TT | RVH+Valsartan |
---|---|---|---|---|
Body Weight (kg) | 48.6±0.6 | 49.1±2.4 | 50.3±2.6 | 48.4±0.7 |
Degree of stenosis (%) | - | 76 ± 8 | 78±5 | 77±6 |
Mean arterial pressure (mmHg) | ||||
Baseline | 108.9±4.5 | 111.1±1.4 | 109.6±1.1 | 107.9±2.9 |
3 wks | 112.2±4.8 | 144.7±8.4* | 134.5±7.6* | 137.5±8.6* |
6 wks | 111.6±4.7 | 163.1±11.8* | 146.9±8.8* | 151.1±10.4* |
10 wks | 107.6±4.9 | 169.8±7.3* | 132.2±10.7*†‡ | 133.1±5.8*†‡ |
Serum Creatinine (mg/dl) | 1.2±0.0 | 1.6±0.1* | 1.7±0.1* | 1.6±0.0* |
Plasma aldosterone (pg/ml) | 586.9±30.0 | 897.2±62.3* | 743.5±86.2* | 697.3±61.5 |
Data are mean±SEM.
p<0.05 vs. Normal;
p<0.05 vs. 6 weeks;
p<0.05 vs. RVH.