Table 3.
Meta association | SNP | Study a | Allele1 | Allele2 | Freq Allele 1 | Min Freq | Max Freq | Weight b | Z score c | P value |
---|---|---|---|---|---|---|---|---|---|---|
White non-Hispanic | rs1052553 | 1,2,3 | A | G | 0.74 | 0.71 | 0.8 | 1722 | 0.19 | 0.849 |
White non-AJ | rs1052553 | 1,2,3 | A | G | 0.75 | 0.71 | 0.8 | 1573 | 0.18 | 0.857 |
Merged association | SNP | Study | Allele1 | Allele2 | Freq Allele1 in cases | Freq Allele1 in controls | OR | L95 | U95 | P |
White non-Hispanic | rs1052553 | 1,2,3 | A | G | 0.76 | 0.75 | 1.03 | 0.88 | 1.20 | 0.754 |
White non-AJ | rs1052553 | 1,2,3 | A | G | 0.75 | 0.80 | 0.72 | 0.50 | 1.03 | 0.074 |
Only rs1052553 was genotyped in all studies.
1, in this study, 2, Vilariño-Güell et al., 3, García-Martín et al.
Weight represents the total number of subjects genotyped
The direction of the Z score represents allelic association with allele 1