Table 2.
Values measured within effective perfusate during study phase without (HP-Control) and with (HP-NaCl, HP-Ri-Ac, HP-6% HES, HP-10% HES and HP-Gel) infusion of respective preparation according to the study protocol
| HP-Control | HP-NaCl | HP-Ri-Ac | HP-6% HES | HP-10% HES | HP-Gel | Unit of measurement | |
|---|---|---|---|---|---|---|---|
| Sodium | 139 ± 1 | 148 ± 2*# | 133 ± 2* | 134 ± 4* | 136 ± 2* | 136 ± 2* | mmol/l |
| Potassium | .3.78 ± 0.04 | .1.77 ± .0.05*# | .4.41 ± .0.09* | .4.46 ± .0.12* | .4.49 ± .0.09* | .4.21 ± .0.09* | mmol/l |
| Calcium | .1.86 ± 0.05 | .0.97 ± .0.04*# | .1.33 ± .0.02* | .1.39 ± .0.05* | .1.44 ± .0.04* | .1.49 ± .0.11* | mmol/l |
| Osmolarity | 269 ± 26 | 266 ± 34 | 256 ± 24 | 274 ± 16 | 276 ± 25 | 276 ± 5 | mosmol/l |
| pH | .7.43 ± 0.04 | .7.38 ± .0.06 | .7.33 ± .0.03* | .7.14 ± .0.04* | .7.08 ± .0.04* | .7.25 ± .0.03* |
Electrolyte concentrations, osmolarity and pH in perfusate, assessed in the delivering lines of the HP groups under basal conditions (HP-Control) and after having switched to infusion mode using the respective study solutions (HP-NaCl, HP-Ri-Ac, HP-6% HES, HP-10% HES, and HP-Gel). All data expressed in mean ± SD; n = 6 for each group; *P <0.001 versus HP-Control; #P <0.001 versus HP-Ri-Ac, HP-6% HES, HP-10% HES, and HP-Gel. HP, heart performance; NaCl, isotonic saline; Ri-Ac, ringer's acetate; 6% and 10% HES: 6% and 10% hydroxyethyl starch in Ringer's acetate.