Table 3.
Patient-reported symptoms and rescue-medication use
| Total n=4,343 |
USA n=1,001 |
MEX n=328 |
BRA n=300 |
FR n=300 |
GER n=300 |
IT n=302 |
SPA n=303 |
UK n=305 |
NL n=303 |
RUS n=301 |
JAP n=300 |
SK n=300 |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rescue-medication use to relieve daytime symptoms, % using every day or most days∧ | 41 | 55 | 37 | 31 | 36 | 47 | 29 | 56 | 72 | 46 | 21 | 37 | 11 |
| Awakenings due to symptoms* at night, % using every night or most nights∧ | 41 | 44 | 48 | 49 | 41 | 34 | 46 | 49 | 55 | 34 | 39 | 30 | 23 |
| Nighttime rescue-medication use to relieve symptoms, % using every night or most nights∧ | 27 | 35 | 35 | 31 | 28 | 23 | 19 | 33 | 60 | 16 | 13 | 16 | 8 |
| CAT score, mean (SD) mMRC grade | 21.5(9.2) | 23.3 (8.9) | 23.9 (8.3) | 24.7 (8.2) | 18.3 (9.7) | 19.3 (8.2) | 19.9(9.7) | 18.4(9.2) | 24.6 (9.7) | 17.2 (8.8) | 22.2 (7.4) | 16.0(9.2) | 24.2 (7.7) |
| 0–1 | 53 | 46 | 45 | 41 | 54 | 62 | 46 | 53 | 38 | 68 | 61 | 73 | 52 |
| ≥2 | 47 | 54 | 55 | 59 | 46 | 38 | 54 | 47 | 62 | 32 | 39 | 27 | 48 |
Notes:
∧
During worst month in previous 12 months;
*
coughing, wheezing or shortness of breath. mMRC: modified Medical Research Council dyspnea grade; 0: ‘only breathless with strenuous exercise’; 1: ‘breathless when hurrying on level or up a slight hill’; 2: ‘walk slower than people of same age on the level due to breathlessness or stop for breath when walking on level at own pace’; 3: ‘stop for breath after walking 100 yards or a few minutes on the level’; 4: ‘too breathless to leave house or breathless when dressing’.