Table 2.
Factors associated with in-hospital mortality among patients with acute kidney injury or end-stage renal disease
| Odds ratio | 95% CI | P-value | |
|---|---|---|---|
| A: Acute kidney injury | |||
| Age >60 years | 1.6 | 1.2, 2.2 | 0.002 |
| Female | 0.96 | 0.71, 1.3 | 0.82 |
| White race | 0.87 | 0.60, 1.2 | 0.43 |
| Medical ICU | 1.2 | 0.9, 1.6 | 0.19 |
| Lactate >4 mmol/L | 2.4 | 1.7, 3.3 | <0.001 |
| Albumin >3 g/dL | 0.83 | 0.61, 1.1 | 0.26 |
| BUN > 30 mg/dL (at admission) | 1.1 | 0.81, 1.5 | 0.54 |
| Creatinine >2 mg/dL (at admission) | 0.76 | 0.56, 1.0 | 0.08 |
| BUN >50 mg/dL (at CRRT initiation) | 1.3 | 0.94, 1.7 | 0.12 |
| Creatinine >3 mg/dL (at CRRT initiation) | 0.56 | 0.41, 0.77 | <0.001 |
| Charlson score >3 | 1.6 | 1.1, 2.3 | 0.006 |
| Liver disease | 1.8 | 1.2, 2.8 | 0.005 |
| B: ESRD | |||
| Age >60 years | 0.88 | 0.45, 1.7 | 0.72 |
| Female | 1.2 | 0.60, 2.5 | 0.57 |
| White race | 0.60 | 0.25, 1.4 | 0.24 |
| Medical ICU | 2.4 | 1.1, 4.9 | 0.02 |
| Lactate >4 mmol/L | 1.5 | 0.28, 7.6 | 0.65 |
| Albumin >3 g/dL | 0.79 | 0.24, 2.6 | 0.70 |
| Charlson score >3 | 2.4 | 1.0, 5.7 | 0.05 |
| Liver disease | 3.7 | 1.2, 11.8 | 0.03 |
(A) Acute kidney injury (AKI) (n = 725). (B) End-stage renal disease (ESRD) (n = 138). BUN, blood urea nitrogen; CRRT, continuous renal replacement therapy.