Table 2.
Sham | Sham | Severe shock/RS | Severe shock/RL | Moderate shock/RS | Moderate shock/RL | |
---|---|---|---|---|---|---|
Parameter |
T = 20 minutes |
T = 280 minutes |
T = 170 minutes |
T = 170 minutes |
T = 230 minutes |
T = 230 minutes |
Hematocrit (%) |
40.2 ± 0.24 |
32.01 ± 0.86 |
21.2 ± 0.7 |
21.3 ± 0.7 |
23.3 ± 1.2 |
23.8 ± 1.0 |
Na
+
(mmol/l) |
138.8 ± 0.3 |
138.5 ± 0.5 |
141.1 ± 0.8 |
138.3 ± 0.9 |
140.7 ± 1.2 |
138.8 ± 0.8 |
Ca
2+
(mmol/l) |
1.4 ± 0.01 |
1.4 ± 0.02 |
1.5 ± 0.03 |
1.5 ± 0.02 |
1.4 ± 0.04 |
1.4 ± 0.03 |
K
+
(mmol/l) |
5.1 ± 0.05 |
5.5 ± 0.2 |
5.6 ± 0.1 |
5.6 ± 0.2 |
5.9 ± 0.3 |
5.6 ± 0.2 |
Cl - (mmol/l) | 105 ± 0.6 | 111 ± 0.9 | 121 ± 0.6 | 117 ± 0.9*# | 122 ± 2.3 | 116 ± 1.5*# |
Rats were subjected to moderate or severe hemorrhage and then resuscitated with either Ringer-saline (RS) or Ringer-lactate (RL). Electrolyte and hematocrit concentrations were measured before shock induction (baseline, T = 10 minutes), at the end of the experiment (sham group; shock/RS, shock/RL; T = 280 minutes) or at T = 150 minutes (that is, the last blood sample taken before the earliest death in the groups to be compared, shock/RS and shock/RL). The baseline values of the sham group were not significantly different from those of the other groups. Values are shown as the means ± SEM. *P <0.05 (vs. moderate shock/RS); # P <0.05 (vs. severe shock/RS).