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. 2013 Jan 29;17(1):R19. doi: 10.1186/cc12493

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Copyright © 2013 Matsuo et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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cRGD lowers the inflammatory response after intestinal ischemia/reperfusion. Blood and tissues were harvested 4 hours after intestinal ischemia/reperfusion (I/R). (A) Serum levels of IL-6 and TNF-α were determined by ELISA. (B) Gut and (C) lung levels of IL-6 and macrophage inflammatory protein-2 (MIP-2) were determined by ELISA. Data expressed as mean ± standard error (n = 5/group). *P < 0.05 versus sham, ^#P < 0.05 versus vehicle. ND, nondetectable. cRGD, cyclic arginine-glycine-aspartate peptide.