Table 2.
Comparison of subjects with chronic kidney disease (CKD) estimated by the Cockcroft-Gault, abbreviated MDRD and CKD-EPI equations
| Cockcroft-Gault | Abbreviated MDRD | CKD-EPI | P -value | |
|---|---|---|---|---|
| Frequency CKD stage 3 or higher, N (%) |
80 (23.7%) |
74 (21.1%) |
76 (21.7%) |
<0.001 |
| Stage 3 (30–59 mL/min/1.73 m2) |
78 (97.5%) |
73 (98.7%) |
75 (98.7%) |
0.9 |
| Stage 4 (15–29 mL/min/1.73 m2) |
2 (2.5%) |
1 (1.4%) |
1 (1.3%) |
0.8 |
| Stage 5 (<15 mL/min/1.73 m2) |
0 |
0 |
0 |
0.9 |
| Serum creatinine, μmol/L, median (IQR) |
97 (80, 115) |
106 (88, 124) |
106 (88, 124) |
<0.001c |
| Estimated glomerular filtration rate, median (IQR) | 47.5 (41, 55) | 53 (45, 55) | 52 (47, 57) | <0.001c |
IQR interquartile range (25th, 75th percentile).
cQuantile regression to compare medians.
MDRD Modification of Diet in Renal Disease Study.
CKD-EPI Chronic Kidney Disease Epidemiology Collaboration.