Table 4.

Various liver transplant criteria (e.g. poor prognosis without transplantation)

Criteria name	OLT criteria (fatal outcome likely without OLT)
Clichy’sa	Grade 3 or 4 encephalopathy with either a decrease of factor V below 30 % of normal in patients > 30 y.o. or a decrease of factor V below 20 % of normal in patients < 30 y.o.
Escudie’sb	Interval between ingestion of mushroom and the onset of diarrhea < 8 h OR decrease in prothrombin index below 10 % of normal (approximately an INR > 6) 4 or more days after ingestion
Ganzert’sb	Prothrombin index < 25 % of normal in conjunction with a serum creatinine > 106 μmol/l (both measured between days 3 and 10 post-ingestion)
King’s College (non-paracetamol)c	INR > 6.5 or any three of the following: patient < 11 y.o. or >40 y.o.; serum bilirubin > 300 μmol/l; time from onset of jaundice to development of coma > 7 days; INR > 3.5; drug toxicity regardless of whether it was the cause of the acute liver failure
King’s College (paracetamol)	Arterial pH below 7.3 or arterial lactate above 3 mmol/l after adequate fluid resuscitation or concurrent serum Cr > 300 μmol/l, INR > 6.5, and grade 3 or 4 encephalopathy

y.o. years old

^aLate in course, King’s criteria more useful

^bCriteria specifically developed for amatoxin

^cNon-paracetamol criteria best