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. 2014 May 6;10(1):21. doi: 10.1186/1710-1492-10-21

Table 3.

Mean change in Asthma Control Questionnaire and Pediatric Asthma Caregivers Quality of Life Questionnaire

Age group Treatment group
Total
Montelukast monotherapy
Montelukast + ICS
Mean SD Mean SD Mean SD
All patients
ACQ score*
Change between Week 4 and Baseline
−0.95
0.88
−1.12
1.03
−1.08
1.00
Change between Week 12 and Baseline
−1.15
0.79
−1.40
1.09
−1.34
1.03
PACQLQ score*
Change between Week 4 and Baseline
0.98
1.12
1.34
1.34
1.25
1.30
Change between Week 12 and Baseline
1.13
1.04
1.78
1.36
1.63
1.32
Emotional function *
Change between Week 4 and Baseline
0.90
1.14
1.25
1.32
1.17
1.29
Change between Week 12 and Baseline
1.02
1.01
1.71
1.41
1.55
1.36
Activity limitation *
Change between Week 4 and Baseline
1.16
1.32
1.53
1.61
1.44
1.55
Change between Week 12 and Baseline
1.38
1.34
1.94
1.51
1.81
1.49
Pre-School patients
ACQ score*
Change between Week 4 and Baseline
−0.89
1.10
−1.38
1.08
−1.26
1.11
Change between Week 12 and Baseline
−1.13
0.94
−1.56
1.16
−1.45
1.12
PACQLQ score*
Change between Week 4 and Baseline
1.01
1.19
1.73
1.42
1.55
1.40
Change between Week 12 and Baseline
1.18
1.06
2.03
1.30
1.82
1.30
Emotional function *
Change between Week 4 and Baseline
0.88
1.16
1.60
1.41
1.42
1.39
Change between Week 12 and Baseline
1.05
0.95
1.94
1.34
1.72
1.31
Activity limitation *
Change between Week 4 and Baseline
1.29
1.40
2.02
1.62
1.84
1.60
Change between Week 12 and Baseline
1.47
1.47
2.24
1.45
2.05
1.49
School aged patients
ACQ score*
Change between Week 4 and Baseline
−1.01
0.64
−0.93
0.94
−0.94
0.88
Change between Week 12 and Baseline
−1.18
0.64
−1.27
1.02
−1.25
0.95
PACQLQ score*
Change between Week 4 and Baseline
0.96
1.08
1.04
1.20
1.02
1.17
Change between Week 12 and Baseline
1.09
1.03
1.58
1.37
1.47
1.31
Emotional function *
Change between Week 4 and Baseline
0.92
1.14
0.99
1.19
0.97
1.18
Change between Week 12 and Baseline
1.00
1.08
1.53
1.44
1.41
1.38
Activity limitation * Change between Week 4 and Baseline
1.04
1.26
1.15
1.49
1.13
1.44
Change between Week 12 and Baseline 1.29 1.23 1.70 1.52 1.61 1.47

*P < 0.001 for all changes from baseline based on Student’s t-test for Paired Observations.