Table 3.
Age group |
Treatment group |
Total |
|||||
---|---|---|---|---|---|---|---|
Montelukast monotherapy |
Montelukast + ICS |
||||||
Mean | SD | Mean | SD | Mean | SD | ||
All patients | |||||||
ACQ score* |
Change between Week 4 and Baseline |
−0.95 |
0.88 |
−1.12 |
1.03 |
−1.08 |
1.00 |
Change between Week 12 and Baseline |
−1.15 |
0.79 |
−1.40 |
1.09 |
−1.34 |
1.03 |
|
PACQLQ score* |
Change between Week 4 and Baseline |
0.98 |
1.12 |
1.34 |
1.34 |
1.25 |
1.30 |
Change between Week 12 and Baseline |
1.13 |
1.04 |
1.78 |
1.36 |
1.63 |
1.32 |
|
Emotional function
* |
Change between Week 4 and Baseline |
0.90 |
1.14 |
1.25 |
1.32 |
1.17 |
1.29 |
Change between Week 12 and Baseline |
1.02 |
1.01 |
1.71 |
1.41 |
1.55 |
1.36 |
|
Activity limitation
* |
Change between Week 4 and Baseline |
1.16 |
1.32 |
1.53 |
1.61 |
1.44 |
1.55 |
Change between Week 12 and Baseline |
1.38 |
1.34 |
1.94 |
1.51 |
1.81 |
1.49 |
|
Pre-School patients | |||||||
ACQ score* |
Change between Week 4 and Baseline |
−0.89 |
1.10 |
−1.38 |
1.08 |
−1.26 |
1.11 |
Change between Week 12 and Baseline |
−1.13 |
0.94 |
−1.56 |
1.16 |
−1.45 |
1.12 |
|
PACQLQ score* |
Change between Week 4 and Baseline |
1.01 |
1.19 |
1.73 |
1.42 |
1.55 |
1.40 |
Change between Week 12 and Baseline |
1.18 |
1.06 |
2.03 |
1.30 |
1.82 |
1.30 |
|
Emotional function
* |
Change between Week 4 and Baseline |
0.88 |
1.16 |
1.60 |
1.41 |
1.42 |
1.39 |
Change between Week 12 and Baseline |
1.05 |
0.95 |
1.94 |
1.34 |
1.72 |
1.31 |
|
Activity limitation
* |
Change between Week 4 and Baseline |
1.29 |
1.40 |
2.02 |
1.62 |
1.84 |
1.60 |
Change between Week 12 and Baseline |
1.47 |
1.47 |
2.24 |
1.45 |
2.05 |
1.49 |
|
School aged patients | |||||||
ACQ score* |
Change between Week 4 and Baseline |
−1.01 |
0.64 |
−0.93 |
0.94 |
−0.94 |
0.88 |
Change between Week 12 and Baseline |
−1.18 |
0.64 |
−1.27 |
1.02 |
−1.25 |
0.95 |
|
PACQLQ score* |
Change between Week 4 and Baseline |
0.96 |
1.08 |
1.04 |
1.20 |
1.02 |
1.17 |
Change between Week 12 and Baseline |
1.09 |
1.03 |
1.58 |
1.37 |
1.47 |
1.31 |
|
Emotional function
* |
Change between Week 4 and Baseline |
0.92 |
1.14 |
0.99 |
1.19 |
0.97 |
1.18 |
Change between Week 12 and Baseline |
1.00 |
1.08 |
1.53 |
1.44 |
1.41 |
1.38 |
|
Activity limitation * | Change between Week 4 and Baseline |
1.04 |
1.26 |
1.15 |
1.49 |
1.13 |
1.44 |
Change between Week 12 and Baseline | 1.29 | 1.23 | 1.70 | 1.52 | 1.61 | 1.47 |
*P < 0.001 for all changes from baseline based on Student’s t-test for Paired Observations.