Table 3.
Odds ratios and protective efficacy of interventions using an intention to treat analysis, adjusting for household clustering and repeated observation of individuals with mixed-effects logistic regression
| Control | Coils | LLINs | Coils + LLINs | |
|---|---|---|---|---|
| Odds Ratio of being P. falciparum positive |
1 |
0.23 |
0.09 |
0.05 |
| (95% Confidence Interval [CI]) |
- |
(0.10,0.49) |
(0.03, 0.28) |
(0.01, 0.23) |
| Age-adjusted OR |
- |
0.23 |
0.09 |
0.06 |
| (95% CI) |
- |
(0.11, 0.50) |
(0.03, 0.28) |
(0.01, 0.23) |
| p-value§ |
|
0.0002 |
<0.0001 |
<0.0001 |
| Protective efficacy |
|
77% |
91% |
94% |
| (95% CI) |
|
(50, 89) |
(72, 97) |
(77, 99) |
| Odds Ratio of being P. vivax positive |
1 |
0.20 |
0.21 |
0.07 |
| (95% Confidence Interval [CI]) |
- |
(0.09, 0.44) |
(0.10, 0.47) |
(0.02, 0.24) |
| p-value |
- |
<0.0001 |
0.0001 |
<0.0001 |
| Protective efficacy |
|
80% |
79% |
93% |
| (95% CI) | (56, 91) | (53, 90) | (76, 98) |
§P-values for unadjusted and age-adjusted odds ratios were identical.