Table 1.
Patient demographics of xenografts used in this study
| Xenograft | Sex | Age | Cytogenetics | Immunophenotype | Diagnosis WCC | Diagnosis blasts | Day 8 blasts | |
|---|---|---|---|---|---|---|---|---|
| (Months) | (Diagnostic patient sample) | ×109/L | ×109/L | ×109/L | ||||
| PPR | ALL-28 | M | 20 | Hyperdiploid | CD45-/DR+/10+/19+/2-/7-/13-/33+/34+ | 15.0 | 11.8 | 1.9 |
| PPR | ALL-50 | M | 131 | Normal | CD45+/DR+/10+/19+/20+ | 34.6 | 26.1 | 5.5 |
| PPR | ALL-54 | M | 89 | Normal | CD45+/DR+/10+/19+/20+/34+/13-/33- | 185.0 | 174.8 | 1.2 |
| PPR | ALL-55 | M | 176 | t(9;22) | CD45+/DR+/10+/19+/13+/33+/34+ | 422.5 | 388.7 | 22.6 |
| PPR | ALL-57 | F | 72 | t(1;19) | CD45+/DR+/19+/10+/34-2-/7- | 15.9 | 7.2 | 1.6 |
| PGR | ALL-26 | F | 43 | t(12;21) | CD45+/DR+/CD19+/10+/22+/3-/34+/117-/Cu-/TdT+ | 89.4 | 80.5 | 0.0 |
| PGR | ALL-51 | M | 19 | dic(7;9) | CD45+/DR+/CD19+/10+/22+/34-/117-/Cu-/TdT+ | 90.5 | 76.9 | 0.0 |
| PGR | ALL-52 | M | 138 | t(7;15) | CD45+/DR+/CD19+/22+/13+/33+/10-/34-/Cu-/TdT+ | 14.4 | 4.0 | 0.0 |
| PGR | ALL-53 | M | 87 | t(12;21) | CD45+/DR+/10+/19+/34+ | 20.3 | 13.8 | 0.1 |
| PGR | ALL-56 | M | 120 | t(9;22) | CD45-/DR+/10+/19+/34+/2-/7-/13-/33- | 8.5 | 0.1 | 0.0 |