Table 2.
Differential probes associated with prednisolone response
| Probe type | Probe ID | Gene symbol | Adjusted p-value | ACC | DESC |
|---|---|---|---|---|---|
| DNA methylation probes | cg02780988 | KRTHA6 | 0.0001 | NM_003771 | keratin 36 |
| cg16848873 | HOXB6 | 0.0001 | NM_018952 | homeobox B6 | |
| cg00546897 | LOC284837 | 0.0002 | NM_194310 | ||
| cg02789485 | MGC39497 | 0.0007 | NM_152436 | GLI pathogenesis-related 1 like 2 | |
| cg01605783 | LOC284837 | 0.0010 | NM_194310 | ||
| cg20291222 | CAPS2 | 0.0012 | NM_032606 | calcyphosine 2 | |
| cg05724065 | PHKG1 | 0.0019 | NM_006213 | phosphorylase kinase, gamma 1 (muscle) | |
| cg00645579 | IRF7 | 0.0033 | NM_001572 | interferon regulatory factor 7 | |
| cg02100629 | AMID | 0.0158 | NM_032797 | apoptosis-inducing factor, mitochondrion-associated, 2 | |
| cg20649991 | LILRB5 | 0.0170 | NM_006840 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 | |
| cg11952714 | SNX7 | 0.0170 | NM_015976 | sorting nexin 7 | |
| cg20050826 | K6IRS2 | 0.0170 | NM_080747 | keratin 72 | |
| cg21306775 | FLJ44881 | 0.0190 | NM_207461 | ||
| cg20468883 | BNIP2 | 0.0202 | NM_004330 | BCL2/adenovirus E1B 19kDa interacting protein 2 | |
| cg08739282 | DHX15 | 0.0202 | NM_001358 | DEAH (Asp-Glu-Ala-His) box polypeptide 15 | |
| cg03172991 | NFIX | 0.0211 | NM_002501 | nuclear factor I/X (CCAAT-binding transcription factor) | |
| cg19238840 | GP2 | 0.0211 | NM_001007240 | glycoprotein 2 (zymogen granule membrane) | |
| cg10148841 | ROBO4 | 0.0223 | NM_019055 | roundabout homolog 4, magic roundabout (Drosophila) | |
| cg09892390 | ARHGAP21 | 0.0254 | NM_020824 | Rho GTPase activating protein 21 | |
| cg05961212 | ADPRH | 0.0254 | NM_001125 | ADP-ribosylarginine hydrolase | |
| cg22844623 | GJA12 | 0.0254 | NM_020435 | gap junction protein, gamma 2, 47kDa | |
| cg18096388 | PDCD1 | 0.0255 | NM_005018 | programmed cell death 1 | |
| cg05921324 | APOA4 | 0.0255 | NM_000482 | apolipoprotein A-IV | |
| cg13633560 | LRRC32 | 0.0270 | NM_005512 | leucine rich repeat containing 32 | |
| cg19573166 | SLC22A17 | 0.0270 | NM_020372 | solute carrier family 22, member 17 | |
| cg01410472 | CRISPLD1 | 0.0277 | NM_031461 | cysteine-rich secretory protein LCCL domain containing 1 | |
| cg26624914 | AQP3 | 0.0377 | NM_004925 | aquaporin 3 (Gill blood group) | |
| cg23752985 | VAMP8 | 0.0389 | NM_003761 | vesicle-associated membrane protein 8 (endobrevin) | |
| cg21148892 | CLEC4F | 0.0389 | NM_173535 | C-type lectin domain family 4, member F | |
| cg00032666 | CXorf6 | 0.0402 | NM_005491 | mastermind-like domain containing 1 | |
| cg19511844 | ORMDL3 | 0.0418 | NM_139280 | ORM1-like 3 (S. cerevisiae) | |
| cg16127900 | GPRC6A | 0.0466 | NM_148963 | G protein-coupled receptor, family C, group 6, member A | |
| cg12552392 | NFS1 | 0.0475 | NM_181679 | ||
| cg22437699 | ARX | 0.0479 | NM_139058 | aristaless related homeobox | |
| cg02849695 | CCDC19 | 0.0486 | NM_012337 | coiled-coil domain containing 19 | |
| Gene expression probes | ILMN_1806907 | PAWR | 0.0000 | NM_002583 | PRKC, apoptosis, WT1, regulator |
| ILMN_1794046 | MTX2 | 0.0119 | NM_006554 NM_001006635 | Metaxin 2 | |
| ILMN_1758128 | CYGB | 0.0119 | NM_134268 | Cytoglobin | |
| ILMN_1738438 | MAST4 | 0.0157 | NM_198828 | Microtubule associated serine/threonine kinase family member 4 | |
| ILMN_1789384 | QSOX2 | 0.0190 | NM_181701 | Quiescin Q6 sulfhydryl oxidase 2 | |
| ILMN_2306565 | MTX2 | 0.0190 | NM_006554 NM_001006635 | Metaxin 2 | |
| ILMN_2295987 | NBPF1 | 0.0237 | NM_017940 | Neuroblastoma breakpoint family, member 1 | |
| ILMN_1765772 | MYO3A | 0.0305 | NM_017433 | Myosin IIIA | |
| ILMN_1713934 | LITAF | 0.0305 | NM_004862 | Lipopolysaccharide-induced TNF factor | |
| ILMN_1668125 | MYRIP | 0.0305 | NM_015460 | Myosin VIIA and Rab interacting protein | |
| ILMN_1681888 | PRKAR2A | 0.0305 | NM_004157 | Protein kinase, cAMP-dependent, regulatory, type II, alpha | |
| ILMN_2184966 | ZHX2 | 0.0305 | NM_014943 | Zinc fingers and homeoboxes 2 | |
| ILMN_1706505 | COL5A1 | 0.0305 | NM_000093 | Collagen, type V, alpha 1 | |
| ILMN_1656057 | PLAU | 0.0305 | NM_002658 | Plasminogen activator, urokinase | |
| ILMN_1761540 | SEMA3F | 0.0305 | NM_004186 | Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F | |
| ILMN_1753143 | DKFZp761L1918 | 0.0305 | NM_033103 | Homo sapiens rhophilin-like protein mRNA, complete cds. | |
| ILMN_2148944 | ADCY4 | 0.0305 | NM_139247 | Adenylate cyclase 4 | |
| ILMN_1812618 | ARAP3 | 0.0305 | NM_022481 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | |
| ILMN_1681081 | AGPAT2 | 0.0359 | NM_006412 | 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) | |
| ILMN_1743275 | SH3RF3 | 0.0359 | NM_001099289 | SH3 domain containing ring finger 3 | |
| ILMN_1656951 | APCDD1 | 0.0359 | NM_153000 | Adenomatosis polyposis coli down-regulated 1 | |
| ILMN_1719756 | ZAP70 | 0.0359 | NM_207519 NM_001079 | Zeta-chain (TCR) associated protein kinase 70kDa | |
| ILMN_1768732 | SPAG16 | 0.0437 | NM_024532 NM_001025436 | Sperm associated antigen 16 |