Table 1.

Clinical correlation of SREBP-1 expression in HCC (n = 47).

Clinicopathologic	Features	Total No. of Patients, n = 47	No. of Patients		p	r
			SREBP-1 Negative	SREBP-1 Positive
Age (y)	<50	13	3	11	0.508	–0.147
	≥50	34	12	21
Sex	Male	30	11	19	0.353	0.135
	Female	17	4	13
HBV	Absent	8	3	5	0.710	0.054
	Present	39	12	27
Serum AFP level (ng/mL)	<400	22	8	14	0.539	0.090
	≥400	25	7	18
Tumor size (cm)	<5	15	9	6	0.005 *	0.413
	≥5	32	6	26
Cirrhosis	Absent	9	5	4	0.196	0.247
	Present	38	10	28
Venous infiltration	Absent	25	11	14	0.058	0.276
	Present	22	4	18
Number of nodules	1	27	11	16	0.123	0.220
	≥2	20	4	16
Edmondson-Steiner grading	I + II	18	10	8	0.006 *	0.400
	III + IV	29	5	24
TNM tumor stage	I + II	28	13	15	0.010 *	0.378
	III + IV	19	2	17

HCC, hepatocellular carcinoma; HBV, hepatitis B virus; AFP, alpha-fetoprotein; TNM, tumor-node-metastasis;

^*Statistically significant.