Table 5.
Effective permeability of NCE using single-pass intestinal perfusion method. The data were presented as mean ± SD (n = 6 for each group).
| Perfusate (μg/mL) | Peff (10−4 cm/s) | ||
|---|---|---|---|
|
| |||
| Duodeum | Jejunum | Ileum | |
| 2 | 0.21 ± 0.18 | 0.20 ± 0.30 N.S. | 0.23 ± 0.25 N.S. |
| 20 | 0.34 ± 0.12 | 0.30 ± 0.15 N.S. | 0.29 ± 0.10 N.S. |
| 40 | 0.49 ± 0.29 | 0.56 ± 0.26 N.S. | 0.52 ± 0.28 N.S. |
N.S., not significantly different to the group of duodenum segment of NCE at the same concentration or not significantly different to the group of 2 μg/mL of NCE in the same intestinal segment.