Table 3.
Necroinflammation according to HCV genotype and IL28B (CC vs. CT/TT).
| Grading | HCV-1 | HCV-2 | HCV-3 | HCV-4 | ||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| CC (n = 43) | CT/TT (n = 108) | CC (n = 39) | CT/TT (n = 60) | CC (n = 28) | CT/TT (n = 22) | CC (n = 7) | CT/TT (n = 28) | |
| METAVIR A ≥ 2 | 49% | 50% | 54% | 48% | 43% | 45% | 71% | 54% |
| Ishak | ||||||||
| Piecemeal ≥ 3 | 23% | 13% | 28% | 18% | 14% | 10% | 14% | 18% |
| Portal ≥ 3 | 86% | 63% | 69% | 65% | 50% | 55% | 71% | 46% |
| Lobular ≥ 3 | 19% | 19% | 44% | 23% | 21% | 36% | 71% | 29% |
| Confluent ≥ 3 | 23% | 5% | 18% | 7% | 14% | 5% | 0 | 14% |
p-values ns for all comparisons except for severe portal inflammation in HCV-1 (p = 0.005) and severe lobular inflammation in HCV-2 (p = 0.03).