Figure 6.

miR-103 promotes colorectal cancer xenograft growth. (A) Xenograft models (n = 8) in nude mice were generated with transfected HCT-116 cells as indicated. Tumor size was measured every three days for 5 weeks; (B) Xenograft tumors in nude mice were weighed; (C) Relative miR-103 expression in xenografts was analyzed by real-time PCR; and (D) PTEN in tumor tissues from various groups was detected with immunohistochemistry using specific PTEN antibodies (200× magnification). Error bars represent as mean ± SD. ^a p < 0.05; ^b p < 0.01 vs. control.