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Immunohistochemical staining of PPARα (A–C) and PPARγ (D–F) in TSOD mice treated with 4-NQO. Representative slides show a strong increase in PPARα expression in the nuclei of lung proliferative lesions: (A,D): bronchioloalveolar hyperplasia; (B,E): adenoma; and (C,F): adenocarcinoma.
