Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Jun 6;6:19. doi: 10.1186/1757-4749-6-19

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Bereswill et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Cerebral histopathological changes following acute ileitis induction. C57BL/6 wildtype (WT; black circles) and TLR-9 deficient (TLR-9-/-; white circles) mice were perorally infected with 100 cysts of T. gondii ME49 strain on day 0 to induce acute ileitis. Naïve mice served as negative controls (N). Intracerebral (A) IFN-γ, (B) TNF-α, and (C) IL-6 mRNA expression levels were measured in ex vivo brain biopsies applying quantitative RT-PCR. Numbers of analyzed mice (in parentheses), means (black bars), and levels of significance (P-values) determined by Mann–Whitney-U test are indicated. Data shown were pooled from three independent experiments.