Table 1.
Clinicopathologic characteristics of colorectal cancer patients and methylation status of ADHFE1
| Characteristics | No. of cases |
Methylation status of
ADHFE1
(PMR, %) |
|
|---|---|---|---|
| Median (range) | p -Value | ||
| Normal |
73 |
3.25 (±0.50) |
< 0.001† |
| Colorectal cancer |
73 |
74.89 (±8.06) |
|
| Age (years) |
|
|
0.957 |
| ≤ 65 |
35 |
75.35 (±13.73) |
|
| > 65 |
38 |
74.46 (±9.13) |
|
| Gender |
|
|
0.114 |
| Female |
27 |
91.55 (±16.46) |
|
| Male |
46 |
65.10 (±8.21) |
|
| Location |
|
|
0.627 |
| Colon |
46 |
77.91 (±10.45) |
|
| Rectum |
27 |
69.73 (±12.77) |
|
| TNM Stage |
|
|
0.252 |
| I,II |
32 |
85.40 (±14.10) |
|
| III,IV |
41 |
66.68 (±9.18) |
|
| Size (mm) |
|
|
0.276 |
| ≤ 25 |
44 |
67.71 (±7.81) |
|
| > 25 |
29 |
85.78 (±16.48) |
|
| Alcohol consumption |
|
|
0.012† |
| Non-drinking |
36 |
95.27 (±13.15) |
|
| Drinking | 37 | 55.06 (±8.41) | |
Statistical significance is evaluated by analysis of variance (ANOVA). †p-Values of < 0.05 are considered statistically significant.
PMR: Percentage of methylated reference; TNM: Tumor, lymph nodes and metastasis.