Table 4.
IVF/ICSI outcomes of PORs according to different ovarian hyperstimulation protocols and age
| <35 years | ≥35 years | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
|
|
|||||||||
| Long | Short | Super long | Modified super long | Mild | Long | Short | Super long | Modified super long | Mild | |
| No. of cycles | 180 | 10 | 29 | 19 | 25 | 183 | 27 | 21 | 27 | 71 |
| No. of cycles with embryos transferred | 139 | 6 | 23 | 15 | 14 | 135 | 20 | 17 | 21 | 42 |
| Duration of Gn | 11.6 ± 2.1 | 12.3 ± 1.9 | 13.3 ± 2.2* | 13.6 ± 1.7* | 6.5 ± 1.8*,#,Δ,& | 11.6 ± 2.3 | 10.7 ± 2.4 | 12.5 ± 2.6 | 12.6 ± 3.5 | 6.4 ± 2.5*,#,Δ,& |
| Dose of Gn (IU) | 2873.9 ± 1045.1 | 3982.5 ± 1290.1* | 3732.6 ± 1192.6* | 3728.6 ± 859.2* | 854.0 ± 340.5*,#,Δ,& | 3496.2 ± 975.7 | 3732.3 ± 1223.1 | 3500.0 ± 773.3* | 3637.5 ± 1178.1* | 1032.2 ± 1190.5*,#,Δ,& |
| Oocytes retrieved | 2.3 ± 0.7 | 1.9 ± 0.9 | 2.16 ± 0.90 | 2.2 ± 0.8 | 1.9 ± 0.8 | 2.2 ± 0.8 | 2.0 ± 0.8 | 2.21 ± 0.92 | 2.3 ± 0.7 | 1.8 ± 0.7 |
| Embryos transferred | 1.6 ± 0.5 | 1.3 ± 0.8 | 1.5 ± 0.7 | 2.0 ± 0.7 | 1.4 ± 0.6 | 1.6 ± 0.7 | 1.6 ± 0.7 | 1.7 ± 0.8 | 1.5 ± 0.5 | 1.4 ± 0.5 |
| E2 level on day HCG (ng/l) | 1976.2 ± 1140.7 | 1556.8 ± 985.6 | 1367.9 ± 894.3 | 1432.1 ± 1073.2 | 891.6 ± 732.8*,#,Δ,& | 1530.3 ± 956.7 | 918.7 ± 842.1 | 1074.8 ± 921.4 | 1289.7 ± 973.2 | 663.7 ± 589.2 |
| Cancellation rate (%) | 22.8 | 40.0 | 20.7 | 21.1 | 44.0* | 35.6 | 25.9 | 19.0 | 22.2 | 40.8 |
| Implantation rate (%) | 22.0 | 25.0 | 29.4 | 23.6 | 15.3 | 17.1 | 6.3 | 24.1 | 19.1 | 15.0 |
| Clinical pregnancy rate (%) | 28.1 | 33.3 | 39.1 | 34.3 | 21.4 | 25.2 | 10.0 | 35.3 | 29.7 | 19.0 |
*
Compared with long protocol, P<0.05;
#
Compared with short protocol, P<0.05;
Δ
Compared with super long protocol, P<0.05;
&
Compared with modified super long protocol, P<0.05.