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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Drug Alcohol Depend. 2014 Apr 13;140:33–41. doi: 10.1016/j.drugalcdep.2014.03.031

Figure 2.

Figure 2

ROI = region of interest; CB+ = non-abstinent cannabis dependence; CB− = abstinent cannabis dependence; HC = healthy comparison

A shows bilateral structural putamen ROIs (Harvard-Oxford Subortical Structural Atlas).

B shows mean (± standard error) putamen volumes for the right and left putamen among non-abstinent cannabis-dependent participants (CB+), abstinent cannabis-dependent participants (CB−) and healthy comparison (HC) participants.

In comparison to healthy comparison participants, non-abstinent cannabis dependent participants had significantly reduced left and right putamen volumes (F= 7.13, p= .04; F= 5.95, p= .02). After controlling for total tissue volume, these reductions remained significant (F=6.82, p=.01, F=4.69, p=.04). There were no significant differences in left or right putamen volume between abstinent cannabis dependent participants and healthy comparison participants (p’s > .1).