Table 3.
Univariate analysis of clinical and histological parameters on overall survival
| Tumoral and patients characteristics | N | OS (months) | HR | p |
|---|---|---|---|---|
| OMS 0-1 |
32 |
12 |
2.10 |
0.007 |
| Vs 2-3 |
21 |
6.2 |
CI 95% 1.11-3.9 |
|
| Weight loss ≥ 10% |
12 |
3.4 |
2.58 |
0.002 |
| < 10% |
41 |
11 |
CI 95% 1.06-6 |
|
| Adenocarcinoma |
43 |
8.3 |
0.93 |
0.84 - NS |
| Vs others histological subtypes |
12 |
7.8 |
CI 95% 0.49- 1.8 |
|
| TTF1 negative |
22 |
6.4 |
0.54 |
0.03 |
| Vs positive |
28 |
15.4 |
CI 95% 0.29- 1 |
|
| T0-1 |
26 |
15.5 |
2.37 |
0.0013 |
| vs T2-3-4 |
23 |
6.6 |
CI 95% 1.25-4.4 |
|
| No visceral involvement |
25 |
12.6 |
1.8 |
0.025 |
| Vs visceral involvement |
30 |
6.4 |
CI 95% 1–3.13 |
|
| Solitary bone metastasis |
10 |
14.2 |
0.42 |
0.0059 |
| Vs multiple bone and/or visceral metastasis |
45 |
7.6 |
CI 95% 0.23-0.73 |
|
| Revealing site: spine |
19 |
6,3 |
1.72 |
0.054 |
| vs other sites |
36 |
10 |
CI 95% 0.90-3.27 |
|
| Spinal epidural metastasis |
|
|
|
|
| Yes |
9 |
3 |
2.4 |
0.017 |
| No | 46 | 9,7 | CI 95% 0.83-5.95 |