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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: J Invest Dermatol. 2014 Jan 17;134(7):1828–1838. doi: 10.1038/jid.2014.28

Figure 3. Overlap of gene co-expression modules with stratum granulosum and epidermal differentiation transcription factor target genes.

Figure 3

The figures show the proportion of genes in each module overlapping with the genes identified in different independent studies. The top two panels depict overlap of each of the normal- and psoriasis- derived modules with stratum corneum genes identified by Toulza et al. (Toulza et al., 2007), Mattiuzzo et al. (Mattiuzzo et al., 2011), or the union of both studies. The bottom two panels depict overlap with targets of the epidermal differentiation regulators STAU1 and TINCR (Kretz et al., 2012) and with the transcription factors ZNF50 and KLF4 (Sen et al., 2012). The numbers in the parentheses after the names of the studies indicate the number of genes in the corresponding gene sets used in this analysis.