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Tnap expression and activity were evaluated in dermal fibroblasts cultured from WT (Abcc6+/+) and KO (Abcc6−/−) mice of 0.5 and 12 months of age. Data are expressed as mean values ± SD of different measurements were values in cells from WT animals 0.5 month-old were set at 1. A representative Western blot is shown. *p<0.05, KO vs WT of the same age; ## p<0.01 and ### p<0.001, 0.5 vs 12 months within the same genotype.
