Table 2.
SNP | Gene | Chromosome / Risk allele | Group | n | # Studies | OR | 95% CI | P-value | Study P-heterogeneity | Sex P-heterogeneity |
---|---|---|---|---|---|---|---|---|---|---|
rs16891982 | SLC45A2 | 5 / G | Female | 10,160 | 3 | 2.37 | (1.69 - 3.31) | 4.67E-07 | 0.45 | 0.02 |
Male | 5,789 | 2 | 5.50 | (2.94 - 10.28) | 9.53E-08 | 0.34 |
Bold p-values are statistically significant for replication at a Bonferron-corrected threshold of 0.05/8=0.006. SNP rs16891982 was not available in HPFS (male only) or NHS (female only).