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. Author manuscript; available in PMC: 2015 Jun 2.
Published in final edited form as: J Am Geriatr Soc. 2014 Jun 2;62(6):1064–1072. doi: 10.1111/jgs.12845

Table 5.

Odds ratios for the associations of slow gait speed, moderate-to-severe mobility impairment, and high sedentary time with poor sleep quality (PSQI >5), according to effect modifier

Effect Modifier Slow Gait Speed a Moderate-to-Severe High Sedentary Time c
Mobility Impairment b
Poor Sleep Quality (PSQI >5)
OR (95% CI) d P value for Interaction OR (95% CI) d P value for Interaction OR (95% CI) d P value for Interaction
Gender
Female 0.84 (0.64, 1.09) 0.11 0.97 (0.75, 1.26) 0.71 0.83 (0.56, 1.23) 0.77
Male 1.22 (0.83, 1.80) 1.06 (0.73, 1.53) 0.90 (0.58, 1.42)
BMI
≥30 1.07 (0.78, 1.46) 0.23 0.92 (0.68, 1.26) 0.52 1.24 (0.81, 1.91) 0.02
<30 0.82 (0.61, 1.12) 1.06 (0.79, 1.42) 0.62 (0.41, 0.93)
CES-D
≥16 0.92 (0.72, 1.17) 0.62 1.05 (0.83, 1.33) 0.30 0.86 (0.63, 1.19) 0.95
<16 1.06 (0.63, 1.78) 0.78 (0.47, 1.30) 0.84 (0.41, 1.72)
Multimorbidity
Medical conditions ≥2 1.29 (0.94, 1.78) <0.01 1.09 (0.80, 1.50) 0.43 0.94 (0.61, 1.44) 0.59
Medical conditions <2 0.71 (0.53, 0.96) 0.93 (0.69, 1.23) 0.80 (0.54, 1.20)
Polypharmacy
≥ 4 medications 1.02 (0.79, 1.32) 0.23 0.99 (0.77, 1.28) 0.96 0.85 (0.61, 1.19) 0.88
< 4 medications 0.76 (0.50, 1.15) 1.01 (0.68, 1.49) 0.89 (0.50, 1.59)
CNS-based medication
Any 0.99 (0.70, 1.39) 0.70 0.95 (0.68, 1.33) 0.70 0.96 (0.61, 1.51) 0.53
None 0.91 (0.69, 1.21) 1.03 (0.78, 1.36) 0.80 (0.54, 1.17)
Health status e
Reduced 1.30 (0.76, 2.23) 0.20 0.97 (0.57, 1.65) 0.91 0.89 (0.44, 1.80) 0.92
Not reduced 0.89 (0.70, 1.13) 1.00 (0.79, 1.27) 0.85 (0.62, 1.18)

Abbreviations: BMI, body mass index; CES-D, Center for Epidemiologic Studies Depression Scale; CI, confidence interval; CNS, central nervous system; OR, odds ratio; PSQI, Pittsburgh Sleep Quality Index; 3MSE, Modified Mini-Mental Status Exam.

a

400 meter gait speed <0.8 m/s.

b

Short Physical Performance Battery score ≤7.

c

Highest quartile of percent accelerometer wear time with activity <100 counts/min. Limited to participants with at least 5 days of wear time and at least 10 hours on each day.

d

Adjusted for age, gender, non-white, BMI, 3MSE, high level of depressive symptoms (CES-D ≥16), number of medical conditions, polypharmacy, CNS-based medication, use of caffeine/energy drinks, and reduced health status, without the variable that was the effect modifier of interest. See Methods.

e

Reduced health status was defined as a rating of “poor.”