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. 2014 Jun 11;6:72. doi: 10.1186/1758-5996-6-72

Table 1.

Clinical characteristics of study subjects

  NC (n = 64) HP (n = 127) HPO (n = 140) p-value
Age (yr)
 46.9 ± 7.6
 48.2 ± 8.6
 47.7 ± 8.8
 0.602*
Sex (M/F)
 97/43
 84/43
 44/20
 0.852#
BMI (kg/m2)
 22.2 ± 1.3
 22.5 ± 1.7
 27.8 ± 1.9ab
 0.000*
WC (cm)
 81.1 ± 5.4
 83.0 ± 6.7c
 94.7 ± 6.0ab
 0.000*
WHR
 0.88 ± 0.05
 0.90 ± 0.05c
 0.94 ± 0.05ab
 0.000*
SBP (mmHg)
 116.5 ± 11.4
 151.7 ± 11.7a
 155.8 ± 14.7ad
 0.000*
DBP (mmHg)
 74.5 ± 7.7
 97.0 ± 9.4a
 98.8 ± 11.4a
 0.000*
UA (µmol/l)
 294.2 ± 67.7
 323.0 ± 78.8c
 384.8 ± 91.4ab
 0.000*
TG (mmol/l)
 1.39 ± 0.65
 1.93 ± 1.07a
 2.43 ± 1.27ab
 0.000*
TC (mmol/l)
 5.31 ± 0.95
 5.38 ± 0.92
 5.40 ± 0.97
 0.658*
LDL-C (mmol/l)
 2.53 ± 0.60
 2.70 ± 0.58
 2.72 ± 0.63
 0.176*
HDL-C (mmol/l)
 1.60 ± 0.28
 1.53 ± 0.33
 1.42 ± 0.33ab
 0.001*
FBG (mmol/l)
 5.45 ± 0.42
 5.42 ± 0.57
 5.64 ± 0.56bc
 0.003*
FINS (pmol/l)
 8.4 ± 3.90
 10.7 ± 3.57a
 14.6 ± 5.40ab
 0.000*
HOMA-IR
 2.06 ± 1.06
 2.60 ± 1.00a
 3.66 ± 1.40ab
 0.000*
HOMA-β
 87.4 ± 32.7
 119.7 ± 48.8a
 149.5 ± 83.9a
 0.000*
Smoking (%)
 32.8%
 37.0%
 33.6%
 0.788#
Drinking (%) 26.6% 34.7% 51.4%ab 0.001#

Data represent means ± SD or frequency (percentage).

TG, FINS and HOMA-IR were log transformed before analysis.

*Analysis of variance; # chi-squared test.

ap < 0.01 compared with NC.

bp < 0.01 compared with HP.

cp < 0.05 compared with NC.

dp < 0.05 compared with HP.

NC, normal control subject; HP, hypertension with obesity; HPO, HP with obesity; BMI, body mass index; WC, Waist circumference; WHR, waist-to-hip ratio; SBP, systolic blood pressure; DBP, diastolic blood pressure; WHR, waist hip ratio; UA, uric acid; TG, triglyceride; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; FBG, fasting blood glucose; FINS, fasting plasma insulin; HOMA-IR, HOMA-insulin resistance index; HOMA-β, HOMA β cell function index.