Table 2. Clinicopathological features of 78 patients with high and low phosphatase and tensin homolog (PTEN)-expressing mass-forming cholangiocarcinoma patients.
| Factor | PTEN high (n = 39) | PTEN low (n = 39) | P |
|---|---|---|---|
| Age (years) | 61.2 ± 10.8 | 58.3 ± 13.0 | 0.294 |
| Gender | 0.492 | ||
| Male | 15 (38.5) | 18 (46.2) | |
| Female | 24 (61.5) | 21 (53.8) | |
| Symptom | 0.209 | ||
| Positive | 35 (89.7) | 31 (79.5) | |
| Negative | 4 (10.3) | 8 (20.5) | |
| AST (IU/L) | 0.570 | ||
| ≤ 34 | 19 (48.7) | 21 (53.8) | |
| > 34 | 20 (51.3) | 18 (46.2) | |
| ALT (U/L) | 0.820 | ||
| ≤ 36 | 22 (56.4) | 21 (53.8) | |
| > 36 | 17 (43.6) | 18 (46.2) | |
| ALP (U/L) | 0.240 | ||
| ≤ 94 | 10 (25.6) | 14 (35.9) | |
| > 94 | 29 (74.4) | 25 (64.1) | |
| Bilirubin (total) (mg/dL) | 0.555 | ||
| ≤ 1.3 | 33 (84.6) | 31 (79.5) | |
| > 1.3 | 6 (15.4) | 8 (20.5) | |
| Albumin (g/dL) | 0.089 | ||
| ≤ 3.5 | 16 (41.0) | 9 (23.1) | |
| > 3.5 | 23 (59.0) | 30 (76.9) | |
| Serum CEA (ng/mL) | 0.063 | ||
| ≤ 5 | 14 (35.9) | 17 (58.6) | |
| > 5 | 25 (64.1) | 12 (41.4) | |
| Size (cm) | 0.109 | ||
| ≤ 5 | 13 (33.3) | 20 (51.3) | |
| > 5 | 26 (66.7) | 19 (48.7) | |
| Lymph node | 0.101 | ||
| Negative | 21 (53.8) | 28 (71.8) | |
| Positive | 18 (46.2) | 11 (28.2) | |
| Differentiated | 0.188 | ||
| Well | 2 (5.1) | 0 | |
| Moderate | 21 (53.8) | 20 (51.3) | |
| Poorly | 14 (35.9) | 19 (48.7) | |
| Other | 2 (5.1) | 0 | |
| Post-op chemotherapy | 0.819 | ||
| No | 16 (41.0) | 17 (43.6) | |
| Yes | 23 (59.0) | 22 (56.4) | |
| Post-op radiotherapy | 0.498 | ||
| No | 33 (84.6) | 35 (89.7) | |
| Yes | 6 (15.4) | 4 (10.3) |