Figure 2. Building a DNA repair score (^DRscore) for predicting overall survival.

A. The prognostic information provided by the 22 DNA repair genes was summed within a ^DRscore as defined in the Materials and Methods. Patients of the HM cohort were ranked according to increased ^DRscore and a maximum difference in overall survival (OS) was obtained with a ^DRscore = −7.62 splitting patients in a high risk (24.8%) and low risk (75.2%) groups. B. Validation of ^DRscore using the UAMS-TT2 cohort.